Part:BBa_K3619012

cDNA encoding the antimicrobial peptide Temporin-1Ta

cDNA encoding the small alpha-helical antimicrobial peptide Temporin-1Ta. The peptide has a high activity towards gram-positive bacteria, moderate activity against fungi and a low activity towards gram-negative bacteria. It interferes with cell membranes by causing permeabilization [1].

The lethal concentration of Temporin – 1Ta was normally between 1 to 12 uM for tested species [ 2].

Temporins are a group of antimicrobial peptides found in secretions of Rene temporia, European common frog. The peptide group interferes with cell membranes, causing leakage in bacterial cell membranes [3].

For more information of the peptide, see Uniprot record P56917 [1]

Sources:

1. https://www.uniprot.org/uniprot/P56917

2. https://webs.iiitd.edu.in/raghava/cancerppd/refpdf/9022710.pdf

3. https://pubmed.ncbi.nlm.nih.gov/10691983/

Sequence and Features

Assembly Compatibility:

• 10
  COMPATIBLE WITH RFC[10]
• 12
  COMPATIBLE WITH RFC[12]
• 21
  COMPATIBLE WITH RFC[21]
• 23
  COMPATIBLE WITH RFC[23]
• 25
  COMPATIBLE WITH RFC[25]
• 1000
  COMPATIBLE WITH RFC[1000]